Evaluación de la plasticidad cerebral en pacientes con transferencia hipogloso-facial: análisis de 70 casos
Palabras clave:
Hipogloso, Nervios periféricos, Parálisis facial, Plasticidad
Resumen
Introducción: la plasticidad cerebral es clave para recuperar el control volitivo independiente de los músculos de la mímica luego de una anastomosis hipogloso-facial (AHF), de manera que el movimiento de la lengua no genere movimientos sincrónicos de la cara.
Objetivos: evaluar la plasticidad cerebral mediante el empleo de la escala de plasticidad (PGS).
Materiales y métodos: se evaluaron 70 pacientes luego de una AHF en dos pasos: 1) usando el comando del nervio donante, es decir moviendo la lengua, y 2) activando el músculo de la mímica, evitando conscientemente el uso del comando motor del nervio hipogloso. Se utilizó una escala de plasticidad (PGS) de 4 puntos para evaluar el control voluntario.
Resultados: 29 pacientes obtuvieron un PGS de 1; 37, un PGS de 2; 4, un PGS de 3 y ninguno alcanzó un PGS de 4. Se observó una relación negativa significativa (p <0.01) entre la edad y la plasticidad cerebral, lo que implica que, a mayor edad, menor plasticidad. También se encontró una relación positiva significativa (p <0.05) entre la calidad/frecuencia de la rehabilitación motora y la plasticidad cerebral, sugiriendo que una mejor rehabilitación se asocia con mayor plasticidad.
Conclusión: luego de la evaluación, se observó que la edad tiene una relación negativa y la calidad/frecuencia de la rehabilitación una relación positiva con la plasticidad cerebral. Sin embargo, ningún paciente alcanzó la plasticidad necesaria para un control voluntario independiente y completo.
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Citas
1. Brown S, Isaacson B, Kutz W, Barnett S, Rozen SM. Facial Nerve Trauma: Clinical Evaluation and Management Strategies. Plast Reconstr Surg. 2019 May;143(5):1498–512.
2. Rosenwasser RH, Liebman E, Jim??nez DF, Buchheit WA, Andrews DW. Facial reanimation after facial nerve injury. Neurosurgery. 1991 Oct;568.
3. Pitty LF, Tator CH. Hypoglossal-facial nerve anastomosis for facial nerve palsy following surgery for cerebellopontine angle tumors. J Neurosurg. 1992 Nov;77(5):724–31.
4. Mualem W, Alexander AY, Bambakidis P, Michalopoulos GD, Kerezoudis P, Link MJ, et al. Predictors of favorable outcome following hypoglossal-to-facial nerve anastomosis for facial nerve palsy: a systematic review and patient-level analysis of a literature-based cohort. J Neurosurg. 2022 Aug 1;1–9.
5. Marzo SJ, Leonetti JP, Petruzzelli G. Facial Paralysis caused by Malignant Skull Base Neoplasms. Ear Nose Throat J. 2002 Dec 1;81(12):845–9.
6. Hohman MH, Bhama PK, Hadlock TA. Epidemiology of iatrogenic facial nerve injury: a decade of experience. Laryngoscope [Internet]. 2014 [cited 2024 Jul 6];124(1):260–5. Available from: https://pubmed.ncbi.nlm.nih.gov/23606475/
7. Hayashi A, Nishida M, Seno H, Inoue M, Iwata H, Shirasawa T, et al. Hemihypoglossal nerve transfer for acute facial paralysis. J Neurosurg [Internet]. 2013 Jan [cited 2024 Jul 6];118(1):160–6. Available from: https://pubmed.ncbi.nlm.nih.gov/23101452/
8. Ho AL, Scott AM, Klassen AF, Cano SJ, Pusic AL, Van Laeken N. Measuring Quality of Life and Patient Satisfaction in Facial Paralysis Patients. Plast Reconstr Surg. 2012 Jul;130(1):91–9.
9. Kleiss IJ, Hohman MH, Susarla SM, Marres HAM, Hadlock TA. Health‐related quality of life in 794 patients with a peripheral facial palsy using the FaCE Scale: a retrospective cohort study. Clinical Otolaryngology. 2015 Dec 18;40(6):651–6.
10. Robla-Costales D, Robla-Costales J, Socolovsky M, Di Masi G, Fernández J, Campero Á. Cirugía de la parálisis facial. Conceptos actuales. Neurocirugia. 2015 Sep 1;26(5):224–33.
11. Hamdi OA, Jones MK, Ziegler J, Basu A, Oyer SL. Hypoglossal Nerve Transfer for Facial Nerve Paralysis: A Systematic Review and Meta-Analysis. Facial Plast Surg Aesthet Med [Internet]. 2024 Apr 1 [cited 2024 Jul 10];26(2):219–27. Available from: https://pubmed.ncbi.nlm.nih.gov/38153410/
12. Spector JG. Neural repair in facial paralysis: clinical and experimental studies. Eur Arch Otorhinolaryngol [Internet]. 1997 [cited 2024 Jul 6];254 Suppl 1(SUPPL. 1). Available from: https://pubmed.ncbi.nlm.nih.gov/9065632/
13. Gidley PW GBRJ. Facial nerve grafts: from cerebellopontine angle and beyond. Otol. 1999;20(781):8.
14. Socolovsky M, Malessy M. Brain changes after peripheral nerve repair: limitations of neuroplasticity. J Neurosurg Sci [Internet]. 2021 Aug 1 [cited 2024 Jun 15];65(4):421–30. Available from: https://pubmed.ncbi.nlm.nih.gov/33709667/
15. Hontanilla B, Cabello A. Spontaneity of smile after facial paralysis rehabilitation when using a non-facial donor nerve. J Craniomaxillofac Surg [Internet]. 2016 [cited 2024 Jul 10];44(9):1305–9. Available from: https://pubmed.ncbi.nlm.nih.gov/27460946/
16. Anastakis DJ, Malessy MJA, Chen R, Davis KD, Mikulis D. Cortical Plasticity Following Nerve Transfer in the Upper Extremity. Hand Clin. 2008 Nov;24(4):425–44.
17. Malessy MJA, Hoffmann CFE, Thomeer RTWM. Initial report on the limited value of hypoglossal nerve transfer to treat brachial plexus root avulsions. J Neurosurg [Internet]. 1999 [cited 2024 Jul 6];91(4):601–4. Available from: https://pubmed.ncbi.nlm.nih.gov/10507381/
18. Socolovsky M, Barillaro K, Bonilla G, Masi G Di, Malessy M. Nerve transfers for brachial plexus injuries: grading of volitional control. J Neurosurg. 2022 Sep 1;1–7.
19. Socolovsky M, Di Masi G, Battaglia D. Use of long autologous nerve grafts in brachial plexus reconstruction: factors that affect the outcome. Acta Neurochir (Wien). 2011 Nov 25;153(11):2231–40.
20. Yeole U, Ferrucci L, Murga H, Socolovsky M. Partial hypoglossal-facial neurorrhaphy: a surgical technique. Neurosurgical Focus: Video [Internet]. 2023 Jan 1 [cited 2024 Jul 10];8(1):V14–V14. Available from: https://europepmc.org/articles/PMC9815207
21. Campero A, Socolovsky M. Facial reanimation by means of the hypoglossal nerve: anatomic comparison of different techniques. Neurosurgery [Internet]. 2007 Sep [cited 2024 Jul 10];61(3 Suppl). Available from: https://pubmed.ncbi.nlm.nih.gov/17876232/
22. Socolovsky M, Martins RS, di Masi G, Bonilla G, Siqueira M. Treatment of complete facial palsy in adults: comparative study between direct hemihypoglossal-facial neurorrhaphy, hemihipoglossal-facial neurorrhaphy with grafts, and masseter to facial nerve transfer. Acta Neurochir (Wien) [Internet]. 2016 May 1 [cited 2024 Jul 10];158(5):945–57. Available from: https://pubmed.ncbi.nlm.nih.gov/26979182/
23. Martins RS, Socolovsky M, Siqueira MG, Campero A. HEMIHYPOGLOSSAL–FACIAL NEURORRHAPHY AFTER MASTOID DISSECTION OF THE FACIAL NERVE. Neurosurgery. 2008 Aug;63(2):310–7.
24. Socolovsky M, di Masi G, Bonilla G, Lovaglio A, Battaglia D, Rosler R, et al. Brain plasticity in neonatal brachial plexus palsies: quantification and comparison with adults’ brachial plexus injuries. Child’s Nervous System. 2023 Jul 12;
25. Havton LA, Carlstedt T. Repair and rehabilitation of plexus and root avulsions in animal models and patients. Curr Opin Neurol [Internet]. 2009 Nov [cited 2024 Jul 6];22(6):570–4. Available from: https://journals.lww.com/co-neurology/fulltext/2009/12000/repair_and_rehabilitation_of_plexus_and_root.3.aspx
26. Scott KR, Ahmed A, Scott L, Kothari MJ. Rehabilitation of brachial plexus and peripheral nerve disorders. In 2013. p. 499–514.
27. Couzan S, Martin JM, Chave É, Le Hello C. Update on the thoracic outlet syndrome and plexus brachial syndrome: Specific clinical examination (for all) and rehabilitation protocol. JMV-Journal de Médecine Vasculaire. 2021 Oct;46(5–6):232–40.
28. Milicin C, Sîrbu E. A comparative study of rehabilitation therapy in traumatic upper limb peripheral nerve injuries. NeuroRehabilitation. 2018 Jan 30;42(1):113–9.
29. SAFOURY YA, Eldesoky MT, Abutaleb EE, Atteya MR, Gabr AM. Postoperative physical therapy program for latissimus dorsi and teres major tendons transfer to rotator cuff in children with obstetrical brachial plexus injury. Eur J Phys Rehabil Med. 2017 May;53(2).
30. Janssen RMJ STIJ. Reflections of patients and therapists on a multidisciplinary rehabilitation programme for persons with brachial plexus injuries. Disabil Rehabil. 2019;41(12):1427–34.
2. Rosenwasser RH, Liebman E, Jim??nez DF, Buchheit WA, Andrews DW. Facial reanimation after facial nerve injury. Neurosurgery. 1991 Oct;568.
3. Pitty LF, Tator CH. Hypoglossal-facial nerve anastomosis for facial nerve palsy following surgery for cerebellopontine angle tumors. J Neurosurg. 1992 Nov;77(5):724–31.
4. Mualem W, Alexander AY, Bambakidis P, Michalopoulos GD, Kerezoudis P, Link MJ, et al. Predictors of favorable outcome following hypoglossal-to-facial nerve anastomosis for facial nerve palsy: a systematic review and patient-level analysis of a literature-based cohort. J Neurosurg. 2022 Aug 1;1–9.
5. Marzo SJ, Leonetti JP, Petruzzelli G. Facial Paralysis caused by Malignant Skull Base Neoplasms. Ear Nose Throat J. 2002 Dec 1;81(12):845–9.
6. Hohman MH, Bhama PK, Hadlock TA. Epidemiology of iatrogenic facial nerve injury: a decade of experience. Laryngoscope [Internet]. 2014 [cited 2024 Jul 6];124(1):260–5. Available from: https://pubmed.ncbi.nlm.nih.gov/23606475/
7. Hayashi A, Nishida M, Seno H, Inoue M, Iwata H, Shirasawa T, et al. Hemihypoglossal nerve transfer for acute facial paralysis. J Neurosurg [Internet]. 2013 Jan [cited 2024 Jul 6];118(1):160–6. Available from: https://pubmed.ncbi.nlm.nih.gov/23101452/
8. Ho AL, Scott AM, Klassen AF, Cano SJ, Pusic AL, Van Laeken N. Measuring Quality of Life and Patient Satisfaction in Facial Paralysis Patients. Plast Reconstr Surg. 2012 Jul;130(1):91–9.
9. Kleiss IJ, Hohman MH, Susarla SM, Marres HAM, Hadlock TA. Health‐related quality of life in 794 patients with a peripheral facial palsy using the Fa
10. Robla-Costales D, Robla-Costales J, Socolovsky M, Di Masi G, Fernández J, Campero Á. Cirugía de la parálisis facial. Conceptos actuales. Neurocirugia. 2015 Sep 1;26(5):224–33.
11. Hamdi OA, Jones MK, Ziegler J, Basu A, Oyer SL. Hypoglossal Nerve Transfer for Facial Nerve Paralysis: A Systematic Review and Meta-Analysis. Facial Plast Surg Aesthet Med [Internet]. 2024 Apr 1 [cited 2024 Jul 10];26(2):219–27. Available from: https://pubmed.ncbi.nlm.nih.gov/38153410/
12. Spector JG. Neural repair in facial paralysis: clinical and experimental studies. Eur Arch Otorhinolaryngol [Internet]. 1997 [cited 2024 Jul 6];254 Suppl 1(SUPPL. 1). Available from: https://pubmed.ncbi.nlm.nih.gov/9065632/
13. Gidley PW GBRJ. Facial nerve grafts: from cerebellopontine angle and beyond. Otol. 1999;20(781):8.
14. Socolovsky M, Malessy M. Brain changes after peripheral nerve repair: limitations of neuroplasticity. J Neurosurg Sci [Internet]. 2021 Aug 1 [cited 2024 Jun 15];65(4):421–30. Available from: https://pubmed.ncbi.nlm.nih.gov/33709667/
15. Hontanilla B, Cabello A. Spontaneity of smile after facial paralysis rehabilitation when using a non-facial donor nerve. J Craniomaxillofac Surg [Internet]. 2016 [cited 2024 Jul 10];44(9):1305–9. Available from: https://pubmed.ncbi.nlm.nih.gov/27460946/
16. Anastakis DJ, Malessy MJA, Chen R, Davis KD, Mikulis D. Cortical Plasticity Following Nerve Transfer in the Upper Extremity. Hand Clin. 2008 Nov;24(4):425–44.
17. Malessy MJA, Hoffmann CFE, Thomeer RTWM. Initial report on the limited value of hypoglossal nerve transfer to treat brachial plexus root avulsions. J Neurosurg [Internet]. 1999 [cited 2024 Jul 6];91(4):601–4. Available from: https://pubmed.ncbi.nlm.nih.gov/10507381/
18. Socolovsky M, Barillaro K, Bonilla G, Masi G Di, Malessy M. Nerve transfers for brachial plexus injuries: grading of volitional control. J Neurosurg. 2022 Sep 1;1–7.
19. Socolovsky M, Di Masi G, Battaglia D. Use of long autologous nerve grafts in brachial plexus reconstruction: factors that affect the outcome. Acta Neurochir (Wien). 2011 Nov 25;153(11):2231–40.
20. Yeole U, Ferrucci L, Murga H, Socolovsky M. Partial hypoglossal-facial neurorrhaphy: a surgical technique. Neurosurgical Focus: Video [Internet]. 2023 Jan 1 [cited 2024 Jul 10];8(1):V14–V14. Available from: https://europepmc.org/articles/PMC9815207
21. Campero A, Socolovsky M. Facial reanimation by means of the hypoglossal nerve: anatomic comparison of different techniques. Neurosurgery [Internet]. 2007 Sep [cited 2024 Jul 10];61(3 Suppl). Available from: https://pubmed.ncbi.nlm.nih.gov/17876232/
22. Socolovsky M, Martins RS, di Masi G, Bonilla G, Siqueira M. Treatment of complete facial palsy in adults: comparative study between direct hemihypoglossal-facial neurorrhaphy, hemihipoglossal-facial neurorrhaphy with grafts, and masseter to facial nerve transfer. Acta Neurochir (Wien) [Internet]. 2016 May 1 [cited 2024 Jul 10];158(5):945–57. Available from: https://pubmed.ncbi.nlm.nih.gov/26979182/
23. Martins RS, Socolovsky M, Siqueira MG, Campero A. HEMIHYPOGLOSSAL–FACIAL NEURORRHAPHY AFTER MASTOID DISSECTION OF THE FACIAL NERVE. Neurosurgery. 2008 Aug;63(2):310–7.
24. Socolovsky M, di Masi G, Bonilla G, Lovaglio A, Battaglia D, Rosler R, et al. Brain plasticity in neonatal brachial plexus palsies: quantification and comparison with adults’ brachial plexus injuries. Child’s Nervous System. 2023 Jul 12;
25. Havton LA, Carlstedt T. Repair and rehabilitation of plexus and root avulsions in animal models and patients. Curr Opin Neurol [Internet]. 2009 Nov [cited 2024 Jul 6];22(6):570–4. Available from: https://journals.lww.com/co-neurology/fulltext/2009/12000/repair_and_rehabilitation_of_plexus_and_root.3.aspx
26. Scott KR, Ahmed A, Scott L, Kothari MJ. Rehabilitation of brachial plexus and peripheral nerve disorders. In 2013. p. 499–514.
27. Couzan S, Martin JM, Chave É, Le Hello C. Update on the thoracic outlet syndrome and plexus brachial syndrome: Specific clinical examination (for all) and rehabilitation protocol. JMV-Journal de Médecine Vasculaire. 2021 Oct;46(5–6):232–40.
28. Milicin C, Sîrbu E. A comparative study of rehabilitation therapy in traumatic upper limb peripheral nerve injuries. NeuroRehabilitation. 2018 Jan 30;42(1):113–9.
29. SAFOURY YA, Eldesoky MT, Abutaleb EE, Atteya MR, Gabr AM. Postoperative physical therapy program for latissimus dorsi and teres major tendons transfer to rotator cuff in children with obstetrical brachial plexus injury. Eur J Phys Rehabil Med. 2017 May;53(2).
30. Janssen RMJ STIJ. Reflections of patients and therapists on a multidisciplinary rehabilitation programme for persons with brachial plexus injuries. Disabil Rehabil. 2019;41(12):1427–34.
Publicado
2024-09-01
Cómo citar
[1]
RANC, R.A. de N., Bourguet, M.E., Biancardi, M., Badilla Campos, T.A., Minghinelli, F.E., Iglesias, B. y Socolovsky, M. 2024. Evaluación de la plasticidad cerebral en pacientes con transferencia hipogloso-facial: análisis de 70 casos. Revista Argentina de Neurocirugía. 38, 03 (sep. 2024). DOI:https://doi.org/10.59156/revista.v38i03.663.
Sección
Artículo Original
